Experiencing knee pain can be a debilitating ordeal, hindering one’s mobility and diminishing the overall quality of life. Fortunately, advancements in medical treatments have ushered in the era of viscosupplementation, where knee gel injections have become a beacon of hope for osteoarthritis patients. This minimally invasive procedure involves the injection of a gel-like substance called hyaluronic acid into the knee joint, providing lubrication and potentially offering pain relief and improved function. The journey to recovery, however, does not end with administering these injections.

Post-treatment care is crucial in maximizing the benefits of this innovative therapy. As you navigate the path to regaining your stride with ease, you may wonder, “What should I do after knee gel injections?” The steps you take after this procedure are pivotal, and with expert insights, you can make informed decisions to enhance your rehabilitation process. Are you ready to reclaim the freedom of movement? Continue reading to uncover expert guidelines and personalized strategies to support your recovery journey and restore the spring in your step.

Immediate Post-injection Care

Immediate post-injection care

As with any medical procedure, following the post-injection care instructions provided by your healthcare provider is essential. These instructions may include the following:

Avoid Strenuous Activities

After receiving knee gel injections, it is important to avoid any strenuous activities that could potentially strain the knee joint and impede the healing process. This includes high-impact exercises such as running or jumping, as well as activities that involve heavy lifting or excessive bending of the knees. Instead, opt for low-impact exercises like swimming or cycling to maintain your fitness without putting unnecessary stress on the treated knee.

For instance, if you are an avid runner, consider switching to a low-impact exercise like swimming for a few weeks post-injection. This will give your knee ample time to heal and prevent further complications. The buoyancy of the water in swimming provides a gentle and supportive environment for your joints, allowing you to stay active while minimizing the impact on your knee.

Apply Ice Packs

Your healthcare provider may also recommend applying ice packs to the injected knee for the first few days. This can help reduce swelling and provide effective pain relief. It is important to follow the recommended duration and frequency of application provided by your doctor, as excessive or prolonged use of ice can potentially adversely affect the healing process.

Wrapping the ice pack in a towel or cloth before applying it to your skin is crucial. This precautionary step helps protect your skin from direct contact with the ice, which can cause skin damage or frostbite. By taking this extra measure, you can ensure the safety and effectiveness of using ice packs for pain management.

Take Pain Medication

It is normal to experience some discomfort or pain after receiving knee gel injections. Your healthcare provider may prescribe pain medication or recommend over-the-counter options to manage this symptom. It is crucial to follow the recommended dosage and frequency of taking these medications, as excessive use can lead to adverse effects on your health.

If you have a history of allergies or adverse reactions to certain medications, it is essential to inform your doctor beforehand. They can make necessary adjustments to ensure your safety and comfort as you resume normal activities.

Long-term Post-injection Care

Long-term post-injection care

While immediate post-injection care is crucial, your recovery journey extends beyond the first few days. Adopting healthy habits and practices in the long term is essential to maintain the benefits of knee gel injections and prevent future complications. Here are some tips for long-term post-injection care:

Participate in Physical Therapy

Participating in physical therapy is a vital aspect of long-term post-injection care that can significantly enhance the outcomes of your knee gel injections. A skilled physical therapist will design a personalized rehabilitation program that focuses on strengthening the muscles around your knee, improving flexibility, and increasing the joint’s range of motion. For instance, attending regular physical therapy sessions where you perform an online fitness program targeted exercises that support the healing knee and contribute to its stability and endurance.

Straight leg raises, and wall squats are tailored to bolster the quadriceps and hamstrings without adding undue strain to your knee. Additionally, your therapist may incorporate balance and proprioceptive exercises, essential for preventing future injuries by training your body to respond to changes in terrain and activity. Adhering to a structured physical therapy routine, you will recover more effectively and lay a firm foundation for a more resilient and capable knee.

Maintain a Healthy Weight

Maintaining a healthy weight is crucial to long-term post-injection care for your knee. Excess body weight places additional strain on your joints, particularly the knees, which bear a considerable portion of the body’s weight. Keeping within a healthy weight range effectively reduces the pressure on your knee joint, prolonging the benefits of the gel injections and diminishing the risk of future joint complications.

For instance, incorporating a balanced diet and regular exercise into your lifestyle can significantly contribute to weight management. Partner with a nutritionist to create an eating plan tailored to your needs, and consider activities like walking or yoga that are gentle on the joints. Not only will this aid in maintaining an optimal weight, but it will also contribute to overall health and wellness, setting you on a path to a more active and fulfilling life post-treatment.

Practice Proper Body Mechanics

Practicing proper body mechanics, especially when performing everyday activities like squatting, bending, or lifting, is essential for protecting your knee joints and maintaining their health post-injection. This involves using correct posture, distributing weight evenly on both legs and avoiding sudden or jerky movements that could strain the treated knee.

For instance, when getting up from a chair, distribute your weight evenly on both feet and use the strength of your leg muscles to raise yourself. Avoid bending at the waist to lift heavy objects; instead, squat down using both legs and keep the object close to your body before standing back up. By incorporating these simple yet effective techniques into your daily routine, you can protect your knee joint from unnecessary strain and maintain its well-being in the long run.

Wear Supportive Footwear

Wearing supportive footwear is another crucial aspect of long-term post-injection care for your knee. Properly fitting shoes with good arch support and cushioning can help distribute your body weight evenly, reducing knee stress. This is particularly important for individuals with flat feet or high arches, as they are more prone to knee pain and injuries.

Consult a podiatrist or orthopedic specialist to determine the best footwear options. They may recommend custom orthotics or shoe inserts that provide additional support and cushioning tailored to your foot’s structure. Investing in proper footwear can reduce the risk of future knee complications and maintain the benefits of your hyaluronic acid injections.

Incorporate Low-Impact Activities

Incorporating low-impact activities into your exercise routine is a great way to stay active while protecting your knee joint post-injection. Low-impact exercises like swimming, cycling, or using an elliptical machine can help improve cardiovascular health and strengthen muscles without placing excessive stress on the knees.

Consult your physical therapist or doctor for recommendations on safe, effective, low-impact exercises to incorporate into your routine. By avoiding high-impact activities like running or jumping, you can protect your knee joint from unnecessary strain and maintain its health in the long term.

Consider Alternative Therapies

In addition to physical therapy, there are other alternative therapies that you can consider for long-term post-injection care. These include acupuncture, massage therapy, online video sessions, and chiropractic adjustments, which can help overcome knee pain and promote healing in the treated knee.

Consult your doctor before trying alternative therapies to ensure they align with your treatment plan. They may also recommend specific providers who specialize in working with individuals recovering from knee injuries or surgeries. By incorporating these therapies into your post-injection care, you can enhance the effectiveness of your treatment and maintain a healthy knee for longer.

Practice Good Hygiene

Good hygiene is essential to long-term post-injection care, as it helps prevent infection and further complications in the treated knee. Keep the injection site clean and dry, and avoid submerging it in water until it is fully healed.

If you experience any redness, swelling, or discharge from the hyaluronic acid injection site, consult your doctor immediately to prevent the spread of infection. Maintaining good hygiene practices can minimize the risk of complications and promote a speedy recovery post-injection.

Monitoring for Side Effects

Monitoring for side effects

Monitoring for side effects after receiving gel injections is vital for ensuring the safety and success of the treatment. Be observant for any signs of allergic reactions, such as:


Redness around the injection site can be a common response following a gel injection, but it’s important to differentiate between a normal reaction and one that may indicate a more serious issue. Typically, mild redness is not uncommon and might last for a day or two as the body adjusts to the new substance. However, persistent or spreading redness could be a sign of inflammation or infection, particularly if accompanied by pain or warmth in the area.

For example, if the skin around your knee appears pinker or redder than usual, it’s been several days since your injection. In such a scenario, it’s prudent to consult with your healthcare provider to evaluate the situation. They may check for signs of infection or an allergic reaction to the injection components. It’s essential to monitor the progression of any redness or discomfort you encounter and to provide detailed information to your healthcare professionals, as this will assist in tailoring your care to prevent further complications and ensure optimal outcomes from your treatment.


Some swelling is a normal physiological reaction after a gel injection as the body’s natural healing process begins. However, excessive swelling, particularly if it increases over time or is paired with severe pain, can indicate that the body is not responding well to the treatment. Patients are advised to monitor the affected area closely for changes in size, shape, or tenderness.

For example, mild swelling that subsides a few days after post-injection typically doesn’t raise concern. But, if you observe that the knee becomes more swollen, feels tight, or looks significantly larger than the opposite knee, it would be advisable to seek medical attention. Your doctor might prescribe medications to reduce inflammation or suggest supportive measures such as ice application, compression wraps, or elevation techniques. Excessive swelling could sometimes indicate an allergic reaction to the gel components or an infection. Therefore, reporting any noticeable changes to your doctor for prompt evaluation and appropriate intervention is crucial.


Some degree of discomfort is expected after receiving a gel injection due to the needle puncture and the substance being injected into the joint space. However, if the pain persists or worsens over time, it could indicate a potential problem. For instance, patients might experience mild pain or tenderness during the first few days following knee injections as their bodies get used to the substance.

This can be managed with over-the-counter pain relievers and should improve with time. However, if you notice that your pain levels are not improving or you experience sharp, shooting pains in the affected knee, it’s best to consult with your doctor for further evaluation. They may order imaging tests such as an X-ray or MRI to check for any complications like fractures, tears, or infections that require immediate treatment. It’s essential to keep track of your pain levels and report any significant changes to your healthcare provider to ensure proper management and a successful outcome.

Itching or Rash

Itching or developing a rash around the injection site can indicate an allergic reaction to the gel components. Patients might experience mild itching or redness that subsides within a few days after receiving their injection, but if it persists or becomes severe, it could indicate an allergy. Often, this is accompanied by other symptoms such as swelling and pain.

If you notice any unusual skin changes around the knee, it’s essential to consult with your doctor for assessment. They may prescribe antihistamines or topical creams to manage the itching and prevent further complications. Sometimes, they might recommend an alternative treatment option if you are allergic to the gel used in injections. By monitoring for any signs of allergy and reporting them promptly, you can prevent serious allergic reactions and ensure the safety of your treatment.


Fever is a common immune response to any foreign substance introduced into the body, including gel injections. A mild fever following an injection is normal and should subside within a day or two without intervention. However, developing a high-grade fever or experiencing chills and sweating after injection could indicate a potential infection.

In such cases, patients should seek immediate medical attention to prevent the spread of infection and ensure proper treatment. Your doctor may prescribe antibiotics to manage the fever and any accompanying symptoms. Monitoring your body temperature post-injection and reporting any significant changes or concerns to your healthcare provider for prompt evaluation is essential.

Difficulty Breathing

In rare cases, a gel injection can cause an allergic reaction that affects the respiratory system. Patients might experience difficulty breathing or shortness of breath shortly after receiving their injections, which could be a sign of anaphylaxis. This is a severe and potentially life-threatening allergic reaction that requires immediate medical attention.

If you experience difficulty breathing, chest tightness, wheezing, or swelling of the face or throat after an injection, call 911 or seek emergency medical care immediately. To prevent such situations, informing your healthcare provider about known allergies before receiving a gel injection is crucial. In the case of anaphylaxis, prompt treatment with epinephrine can save lives and prevent further complications.


While gel injections are generally safe and effective for treating knee osteoarthritis, patients must be aware of potential side effects and promptly report any concerns to their healthcare providers. By monitoring for common signs such as swelling, pain, itching or rash, fever, and difficulty breathing, patients can ensure proper management of any complications and achieve the best possible outcomes from their treatment. With proper care and monitoring, gel injections can be a valuable tool in managing knee osteoarthritis and improving patients’ quality of life. So, staying vigilant and communicating any changes or concerns with your doctor is essential for a successful treatment experience.