The Role of Cortisone: What These Injections Really Do
Are you dealing with persistent joint pain or inflammation? What does a cortisone injection do? In simple terms, it offers relief by reducing inflammation and pain in affected areas.
Here’s a quick breakdown:
– Reduces inflammation
– Alleviates pain
– Allows return to daily activities
Cortisone shots primarily target joints such as the hip, knee, shoulder, spine, or wrist. According to Dr. Andrea Halim, a Yale Medicine orthopedic surgeon, they are often used to combat osteoarthritis and tendonitis. Cortisone is a potent corticosteroid that calms the immune system, thus reducing inflammation and pain.
While a cortisone injection can offer significant relief, it doesn’t cure the underlying issue. It’s mainly a treatment to make your life more comfortable and manageable.
I am Robert McLaughlin II, MD, with over 25 years of experience in orthopedic surgery. I specialize in knee and shoulder injuries and have extensive knowledge on what does a cortisone injection do.

What Does a Cortisone Injection Do?
Cortisone injections are like a fire extinguisher for inflammation. They don’t cure the problem but help control the flames.
Immediate Effects
When you get a cortisone shot, you might feel relief pretty quickly. This happens because many cortisone injections also include a numbing medication like lidocaine. The lidocaine kicks in right away, making the shot more comfortable and offering immediate pain relief.
“How the injection feels depends on where you’re getting it,” says Dr. Halim. “Many injections are not painful or only have a few seconds of discomfort.” However, injections into sensitive areas like the palm or soles of the feet might be more uncomfortable.
Long-term Benefits
While the numbing effect is immediate, the cortisone itself takes a bit longer to work. The steroid part of the shot usually starts to kick in after a few days. It reduces inflammation, which can lead to less pain and better mobility.
The relief from a cortisone shot can last for several months. For example, people with conditions like carpal tunnel or trigger finger might experience up to six months of relief. On the other hand, those with arthritis in larger joints like the knee might find the relief lasts a few weeks to a few months.
Targeted Relief
One of the biggest advantages of cortisone injections is their ability to provide targeted relief. Unlike oral medications, which affect your whole body, cortisone shots are injected directly into the problem area. This makes them especially effective for localized issues like arthritis, tendinitis, and bursitis.
For instance, if you have knee osteoarthritis, an intra-articular injection can reduce swelling and pain in that specific joint, allowing you to move more easily. Similarly, soft tissue injections can target inflamed tendons or ligaments, providing relief where you need it most.
Next, we’ll delve into the specific conditions treated by cortisone injections.
Conditions Treated by Cortisone Injections
Cortisone injections are a versatile treatment option for a variety of conditions that involve inflammation and pain. Here’s a closer look at some of the most common conditions they can help manage:
Arthritis
Arthritis is a condition that causes inflammation in the joints, leading to pain and stiffness. Cortisone injections are particularly effective for treating types of arthritis like rheumatoid arthritis and osteoarthritis.
For example, a patient with knee osteoarthritis might receive an intra-articular injection to reduce swelling and alleviate pain, enabling them to walk more comfortably. According to research, cortisone shots can offer relief for several months, although the duration varies from person to person.
Tendinitis
Tendinitis occurs when tendons, the thick cords that attach muscles to bones, become inflamed. This condition often results from repetitive activities or overuse.
A cortisone injection can target the inflamed tendon, reducing pain and swelling. For example, someone suffering from tennis elbow might find significant relief from a cortisone shot, allowing them to resume their daily activities without discomfort.
Bursitis
Bursitis involves the inflammation of the bursae, which are small fluid-filled sacs that cushion bones, tendons, and muscles near joints. Common areas affected include the shoulder, elbow, and hip.
Cortisone injections can be particularly beneficial for reducing inflammation and pain in these areas. For instance, a person with shoulder bursitis might receive an injection that helps them move their arm more freely and with less pain.
Autoimmune Diseases
Autoimmune diseases, such as lupus and psoriatic arthritis, occur when the body’s immune system mistakenly attacks its own tissues. These conditions often cause widespread inflammation and pain.
Cortisone injections can help manage these symptoms by suppressing the immune response in specific areas. This targeted approach can provide significant relief and improve the quality of life for individuals dealing with autoimmune diseases.
Next, we’ll explore how cortisone injections work to provide relief from these conditions.
How Cortisone Injections Work
Mechanism of Action
Cortisone injections are powerful tools for reducing inflammation and pain. But how exactly do they work?
Corticosteroids, like cortisone, are synthetic versions of hormones produced by your adrenal glands. One of these hormones is cortisol, which helps control inflammation in the body. When cortisone is injected directly into an inflamed area, it mimics cortisol’s effects by suppressing the immune system. This reduces the chemicals causing inflammation and, consequently, pain.
Dr. Andrea Halim, an orthopaedic surgeon, explains, “When cortisone is injected into an arthritic joint, it can temporarily ease discomfort related to joint irritation, but it does not regenerate damaged cartilage.” This means the injection helps manage symptoms but doesn’t cure the underlying issue.
Administration Process
Injection Technique
Getting a cortisone shot is straightforward. The procedure is typically done in your doctor’s office and doesn’t require special preparation. However, if you take blood thinners, consult your doctor as you might need to stop taking them for a few days to reduce the risk of bruising or bleeding.
Ultrasound Guidance
For more accuracy, many doctors use ultrasound guidance. This technology allows them to see the exact location where the medication needs to go. Using ultrasound, they can guide the needle precisely to the inflamed area, increasing the likelihood of effective pain relief.
In-Office Procedure
The actual injection process is quick. You’ll feel a brief pinch as the needle goes in, followed by some pressure as the cortisone is injected. Most people find the procedure tolerable, and it’s over in just a few minutes. Afterward, you might feel some soreness at the injection site, but this usually subsides within a day or two.
Next, we’ll look at the potential side effects and risks associated with cortisone injections.
Potential Side Effects and Risks of Cortisone Injections
While cortisone injections can offer significant relief, be aware of potential side effects and risks. Here’s what you need to know:
Short-Term Effects
Immediate Reactions
Some people experience a temporary flare in pain, swelling, and irritation at the injection site. This usually subsides within 48 hours. Applying ice can help alleviate these symptoms.
Facial Flushing and Headaches
A few individuals might notice facial flushing or headaches shortly after the injection. These are generally mild and temporary.
Skin Changes
You might see skin lightening (hypopigmentation) or a small divot (fat necrosis) at the injection site. These changes are usually cosmetic and not harmful.
Long-Term Risks
Tendon Damage
Repeated injections can weaken tendons, potentially leading to tendon rupture. Dr. Halim advises spacing injections at least three months apart and limiting them to a maximum of three per tendon.
Bone and Joint Issues
Long-term use of cortisone injections has been linked to thinning of the bones (osteoporosis) and joint damage. For instance, studies show that corticosteroid injections may worsen the progression of knee osteoarthritis .
Systemic Effects
Blood Sugar Levels
Cortisone can cause temporary elevations in blood sugar, especially in people with diabetes. This effect typically lasts about a week.
Immune System Suppression
Cortisone suppresses the immune system, increasing the risk of infections. This is particularly important to consider if you have surgery planned within two months of an injection.
Monitoring
Signs of Infection
Watch for increasing pain, redness, and swelling that lasts more than 48 hours. These could be signs of an infection, and you should contact your healthcare provider immediately.
Blood Sugar Monitoring
If you have diabetes, monitor your blood sugar closely for a week after the injection.
Preventative Measures
Good Hygiene
Keep the injection site clean and dry. Avoid submerging it in water for two days to prevent infection.
Activity Modification
Avoid strenuous activities and heavy lifting for a couple of days post-injection. This helps minimize the risk of tendon damage and allows the medication to work effectively.
When to Seek Help
If you experience any of the following, seek medical attention:
- Persistent or worsening pain, redness, or swelling
- Signs of infection (fever, chills, or pus at the injection site)
- Significant changes in blood sugar levels
- Severe allergic reactions (though rare)
By being aware of these potential side effects and risks, you can better manage your treatment and ensure optimal outcomes.
Next, we’ll answer some frequently asked questions about cortisone injections.
Frequently Asked Questions about Cortisone Injections
How Long Do Effects Last?
Cortisone injections can offer temporary relief from pain and inflammation. The duration of relief varies depending on the condition being treated. For some, the effects might last a few weeks, while others might experience relief for several months.
For example, trigger finger and carpal tunnel syndrome might see relief for up to six months. On the other hand, conditions like thumb base arthritis can vary widely, with some patients reporting relief for a year and others only for a few weeks.
Chronic conditions like arthritis often require repeated injections for ongoing relief. However, doctors usually recommend spacing these injections out by at least three months to minimize risks.
What Are the Downsides?
While cortisone injections are generally safe, they do come with potential side effects and complications. Common short-term side effects include:
- Facial flushing
- Headaches
- Elevations in blood sugar
More serious but rare complications can include:
- Infection at the injection site
- Fat necrosis (a divot in the skin)
- Hypopigmentation (pale skin at the injection site)
- Tendon damage with repeated injections
It’s also worth noting that while cortisone injections can provide significant relief, they are not usually curative for conditions affecting larger joints like the knees, shoulders, and hips.
What to Expect After an Injection?
Immediate aftermath of a cortisone injection can include a short-term flare in pain, swelling, and irritation for up to two days. After this period, you should notice a reduction in pain and inflammation.
Recovery tips include:
- Use ice on the injection site to relieve pain (avoid heating pads).
- Protect the area for a day or two. For instance, if the injection was in your shoulder, avoid heavy lifting. If it was in your knee, try to stay off your feet as much as possible.
- Avoid baths, hot tubs, or whirlpools for two days. Showers are fine.
- Watch for signs of infection, such as increasing pain, redness, or swelling lasting more than 48 hours.
Activity recommendations include being gentle with the affected area. If you received an injection in your knee, limit strenuous activities and exercise for a few days. Always follow your doctor’s specific advice to ensure the best outcome.
By understanding the duration of effects, potential downsides, and what to expect after an injection, you can better manage your treatment and expectations.
Conclusion
When it comes to managing pain and inflammation, cortisone injections can be a game-changer. The benefits of these injections include quick relief from pain and swelling, improved mobility, and the ability to return to daily activities. For many, this can mean the difference between enduring chronic pain and enjoying life again.
Decision-making around cortisone injections should be a shared process between you and your healthcare provider. It’s crucial to weigh the potential benefits against the risks and side effects. Your doctor will consider your specific condition, overall health, and treatment history to determine if cortisone injections are the right choice for you.
At Boston Concierge Orthopedics, we specialize in providing top-notch care tailored to your needs. Our experienced team uses advanced techniques to ensure the injections are as effective and comfortable as possible. If you’re ready to explore how cortisone injections can improve your quality of life, book an appointment with us today.
By understanding the benefits and making informed decisions, you can take a significant step toward better health and well-being.